THE HORRORS
H1N1
The Spanish flu, also known as La Gripe Española, or La Pesadilla.avian influenza, a viral infectious disease, that killed some 50 million to 100 million people worldwide over about a year in 1918 and 1919. It is thought to be one of the most deadly pandemics in human history
Russian flu of 1977–1978 flu epidemic caused by strain Influenza A/USSR/90/77 (H1N1).
On June 11, 2009, the WHO declared an H1N1 pandemic, moving the alert level to phase 6, marking the first global pandemic since the 1968
H2N2
The 1889 pandemic, known as the Russian Flu, began in Russia and spread rapidly throughout Europe. It reached North America in December 1889 and spread to Latin America and Asia in February 1890. About 1 million people died in this pandemic
The "Asian Flu" OF 1956 was a category 2 flu pandemic outbreak of avian influenza that originated in China in early 1956 lasting until 1958.worldwide death estimates 1-4 million.
H3N2
The Hong Kong Flu was a category 2 flu pandemic caused by a strain of H3N2 descended from H2N2 by antigenic shift, in which genes from multiple subtypes reassorted to form a new virus. This pandemic of 1968 and 1969 killed an estimated one million people worldwide
THE NOMENCLATURE
Influenza, commonly referred to as the flu, is an infectious disease caused by RNA viruses of the family Orthomyxoviridae (the influenza viruses), that affects birds and mammals. The name influenza comes from the Italian influenza, meaning "influence" (Latin: influentia)
In virus classification the influenza virus is an RNA virus of three of the five genera of the family Orthomyxoviridae:
* Influenzavirus A
* Influenzavirus B
* Influenzavirus C
Influenza viruses are classified as type A, B, or C based upon their protein composition.Types A and B have 8 RNA segments and encode 11 proteins. Subtype C has 7 RNA segments and encodes 9 proteins
Influenzavirus A several subtypes, labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 16 different H antigens (H1 to H16) and nine different N antigens (N1 to N9).
hemagglutinin is found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected.The name "hemagglutinin" comes from the protein's ability to cause red blood cells (erythrocytes) to clump together ("agglutinate")
neuraminidase is an enzyme on the surface of influenza viruses that enables the virus to be released from the host cell
The 1,2,3... classification of H and N is because they are protiens,are made of amino acids ,it is the difference between these constituents acids which make them differ.
H1N1
The Spanish flu, also known as La Gripe Española, or La Pesadilla.avian influenza, a viral infectious disease, that killed some 50 million to 100 million people worldwide over about a year in 1918 and 1919. It is thought to be one of the most deadly pandemics in human history
Russian flu of 1977–1978 flu epidemic caused by strain Influenza A/USSR/90/77 (H1N1).
On June 11, 2009, the WHO declared an H1N1 pandemic, moving the alert level to phase 6, marking the first global pandemic since the 1968
H2N2
The 1889 pandemic, known as the Russian Flu, began in Russia and spread rapidly throughout Europe. It reached North America in December 1889 and spread to Latin America and Asia in February 1890. About 1 million people died in this pandemic
The "Asian Flu" OF 1956 was a category 2 flu pandemic outbreak of avian influenza that originated in China in early 1956 lasting until 1958.worldwide death estimates 1-4 million.
H3N2
The Hong Kong Flu was a category 2 flu pandemic caused by a strain of H3N2 descended from H2N2 by antigenic shift, in which genes from multiple subtypes reassorted to form a new virus. This pandemic of 1968 and 1969 killed an estimated one million people worldwide
THE NOMENCLATURE
Influenza, commonly referred to as the flu, is an infectious disease caused by RNA viruses of the family Orthomyxoviridae (the influenza viruses), that affects birds and mammals. The name influenza comes from the Italian influenza, meaning "influence" (Latin: influentia)
In virus classification the influenza virus is an RNA virus of three of the five genera of the family Orthomyxoviridae:
* Influenzavirus A
* Influenzavirus B
* Influenzavirus C
Influenza viruses are classified as type A, B, or C based upon their protein composition.Types A and B have 8 RNA segments and encode 11 proteins. Subtype C has 7 RNA segments and encodes 9 proteins
Influenzavirus A several subtypes, labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 16 different H antigens (H1 to H16) and nine different N antigens (N1 to N9).
hemagglutinin is found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected.The name "hemagglutinin" comes from the protein's ability to cause red blood cells (erythrocytes) to clump together ("agglutinate")
neuraminidase is an enzyme on the surface of influenza viruses that enables the virus to be released from the host cell
The 1,2,3... classification of H and N is because they are protiens,are made of amino acids ,it is the difference between these constituents acids which make them differ.
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